Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTRC | Q99895 | 6/20 | 0.42 |
| ▸ | CMA1 | P23946 | 12/20 | 0.42 |
| ▸ | ELANE | P08246 | 4/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CTSG | P08311 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7951052 | 0.87 | CTRC (0.47) | CTRCCMA1CTSG | |
| SCHEMBL7950527 | 0.87 | CMA1 (0.42) | CTRCCMA1ELANECTSG | |
| SCHEMBL7959687 | 0.86 | ELANE (0.41) | CTRCCMA1ELANE | |
| SCHEMBL7961580 | 0.86 | ELANE (0.47) | CTRCCMA1ELANE | |
| SCHEMBL7960906 | 0.85 | ELANE (0.44) | CTRCCMA1ELANE | |
| SCHEMBL7961591 | 0.83 | ELANE (0.49) | CTRCCMA1ELANE | |
| SCHEMBL7951058 | 0.83 | ELANE (0.49) | CTRCCMA1ELANE | |
| SCHEMBL7961920 | 0.83 | ELANE (0.44) | CTRCCMA1ELANE | |
| SCHEMBL7962497 | 0.82 | ELANE (0.55) | CTRCELANE | |
| SCHEMBL8323709 | 0.82 | ELANE (0.55) | CTRCELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6300337-B1 | Acetamide derivative and use thereof | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2001-10-09 | — | — | US | disclosed |
| EP-1055683-A1 | NOVEL ACETAMIDE DERIVATIVE AND USE THEREOF | Nippon Kayaku Kabushiki Kaisha (JP) | 2000-11-29 | — | — | EP | disclosed |