Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 1/20 | 0.46 |
| ▸ | AKT2 | P31751 | 1/20 | 0.46 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.46 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.43 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.43 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6164711 | 0.82 | FKBP1A (0.59) | AKT1AKT2AKT3HPGDALDH1A1 | |
| SCHEMBL6162739 | 0.82 | FKBP1A (0.59) | AKT1AKT2AKT3HPGDALDH1A1 | |
| 5-Chloroindole-2-Carboxylic Acid SCHEMBL6162973 | 0.75 | CYP51A1 (0.57) | KDM4EALDH1A1MAPT | |
| SCHEMBL6163356 | 0.74 | HDAC8 (0.64) | AKT1AKT2AKT3PIK3CDPIK3CA | |
| SCHEMBL6052947 | 0.74 | HDAC8 (0.64) | AKT1AKT2AKT3PIK3CDPIK3CA | |
| Hydrochloric Acid SCHEMBL6350961 | 0.73 | HDAC8 (0.65) | AKT1AKT2AKT3PIK3CDPIK3CA | |
| Hydrochloric Acid SCHEMBL8307855 | 0.73 | HDAC8 (0.65) | AKT1AKT2AKT3PIK3CDPIK3CA | |
| SCHEMBL14311579 | 0.72 | DPP7 (0.61) | AKT1AKT2AKT3HPGDHTT | |
| SCHEMBL5129878 | 0.72 | TSHR (0.45) | HPGDALDH1A1TSHRSMN1; SMN2LMNA | |
| SCHEMBL6160377 | 0.71 | AKT1 (0.60) | AKT1AKT2AKT3HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6277877-B1 | GLYCOGEN PHOSPHORYLASE INHIBITOR; ANTIDIABETIC AGENTS | PFIZER, INC. | 2001-08-21 | — | — | US | disclosed |