Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | AHR | P35869 | 1/20 | 0.41 |
| ▸ | F2RL3 | Q96RI0 | 3/20 | 0.40 |
| ▸ | ILK | Q13418 | 1/20 | 0.40 |
| ▸ | AXL | P30530 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3642370 | 0.83 | DYRK1A (0.55) | DYRK1ANPC1MAPTRAB9ALMNA | |
| SCHEMBL6982986 | 0.78 | DYRK1A (0.61) | DYRK1ANPC1MAPTRAB9ALMNA | |
| SCHEMBL417526 | 0.78 | DYRK1A (0.54) | DYRK1ANPC1RAB9AAHRF2RL3 | |
| SCHEMBL9385687 | 0.76 | MAPT (0.46) | DYRK1ANPC1MAPTRAB9ALMNA | |
| SCHEMBL9386691 | 0.76 | DYRK1A (0.40) | DYRK1ANPC1MAPTRAB9ALMNA | |
| SCHEMBL9335485 | 0.75 | NPC1 (0.37) | DYRK1ANPC1MAPTRAB9ALMNA | |
| SCHEMBL9387728 | 0.75 | HSD17B10 (0.43) | DYRK1ANPC1MAPTRAB9ALMNA | |
| SCHEMBL9335011 | 0.74 | AKR1B1 (0.40) | DYRK1ANPC1MAPTRAB9ALMNA | |
| SCHEMBL9339006 | 0.74 | MAPT (0.44) | DYRK1ANPC1MAPTRAB9ALMNA | |
| SCHEMBL5572792 | 0.74 | DYRK1A (0.49) | DYRK1ANPC1MAPTRAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010027875-A2 | COMPOUNDS THAT MODULATE INTRACELLULAR CALCIUM | CALCIMEDICA INC. (US) | 2010-03-11 | — | — | WO | disclosed |