Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 7/20 | 0.61 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.47 |
| ▸ | USP7 | Q93009 | 1/20 | 0.46 |
| ▸ | F2RL3 | Q96RI0 | 3/20 | 0.45 |
| ▸ | AHR | P35869 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6983750 | 0.87 | DYRK1A (0.61) | DYRK1APDPK1USP7NPC1RAB9A | |
| SCHEMBL3642370 | 0.85 | DYRK1A (0.55) | DYRK1APDPK1F2RL3AHRNPC1 | |
| SCHEMBL417526 | 0.83 | DYRK1A (0.54) | DYRK1APDPK1F2RL3AHRNPC1 | |
| SCHEMBL28919886 | 0.81 | DYRK1A (0.63) | DYRK1ANPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL24962530 | 0.80 | SMN1; SMN2 (0.57) | DYRK1ASMN1; SMN2MEN1USP2LMNA | |
| SCHEMBL30209129 | 0.80 | SMN1; SMN2 (0.57) | DYRK1ASMN1; SMN2MEN1USP2LMNA | |
| SCHEMBL7961863 | 0.78 | DYRK1A (0.48) | DYRK1AF2RL3AHRNPC1RAB9A | |
| SCHEMBL687516 | 0.76 | THRB (0.50) | DYRK1AAHRNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL687515 | 0.76 | THRB (0.50) | DYRK1AAHRNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6979450 | 0.75 | GAA (0.41) | DYRK1APDPK1USP7NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115504942-A | Synthesis method of alkyl or acyl substituted benzothiazole derivative | 汕头大学 | 2022-12-23 | — | — | CN | disclosed |
| EP-1006114-B1 | PYRAZOLE DERIVATIVES AND COX INHIBITORS CONTAINING THEM | GRELAN PHARMACEUTICAL CO (JP) | 2003-01-22 | — | — | EP | disclosed |
| US-6136831-A | ANTIINFLAMMATORY AGENTS, GASTROINTESTINAL AGENTS, ENZYME INHIBITORS | GRELAN PHARMACEUTICAL CO., LTD. (JP) | 2000-10-24 | — | — | US | disclosed |
| EP-1006114-A1 | PYRAZOLE DERIVATIVES AND COX INHIBITORS CONTAINING THEM | Grelan Pharmaceutical Co., Ltd. (JP) | 2000-06-07 | — | — | EP | disclosed |