Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.49 |
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.45 |
| ▸ | MEN1 | O00255 | 7/20 | 0.45 |
| ▸ | GAA | P10253 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7950033 | 0.86 | ELANE (0.56) | ELANEALDH1A1MAPTL3MBTL1KDM4E | |
| SCHEMBL7958244 | 0.83 | ELANE (0.57) | ELANEALDH1A1MAPTL3MBTL1KDM4E | |
| SCHEMBL7960312 | 0.80 | ELANE (0.50) | ELANEALDH1A1MAPTL3MBTL1KDM4E | |
| Hydrochloric Acid SCHEMBL5207751 | 0.78 | ELANE (0.51) | ELANEALDH1A1MAPTL3MBTL1KDM4E | |
| SCHEMBL7959726 | 0.78 | ELANE (0.53) | ELANEALDH1A1MAPTL3MBTL1KDM4E | |
| SCHEMBL5207629 | 0.76 | MAPT (0.65) | ELANEALDH1A1MAPTL3MBTL1KDM4E | |
| SCHEMBL7960034 | 0.76 | ELANE (0.49) | ELANEALDH1A1MAPTL3MBTL1KDM4E | |
| SCHEMBL27509489 | 0.76 | ELANE (0.49) | ELANEALDH1A1MAPTL3MBTL1KDM4E | |
| SCHEMBL1308058 | 0.76 | KMT2A (0.59) | ELANEALDH1A1MAPTL3MBTL1KDM4E | |
| SCHEMBL7960609 | 0.75 | ESR1 (0.55) | ELANEALDH1A1MAPTL3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6184245-B1 | Cyclic ketone derivatives and their medical applications | TORAY INDUSTRIES INC. (JP) | 2001-02-06 | — | — | US | disclosed |