Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.55 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.55 |
| ▸ | ELANE | P08246 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | TYR | P14679 | 1/20 | 0.46 |
| ▸ | DAO | P14920 | 1/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.45 |
| ▸ | MEN1 | O00255 | 6/20 | 0.45 |
| ▸ | CA12 | O43570 | 3/20 | 0.45 |
| ▸ | CA9 | Q16790 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | GAA | P10253 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7950033 | 0.80 | ELANE (0.56) | ESR2ELANEHPGDKMT2AMEN1 | |
| SCHEMBL7949844 | 0.79 | LMNA (0.56) | ESR1ESR2HPGDTYRDAO | |
| SCHEMBL7959726 | 0.78 | ELANE (0.53) | ESR2ELANEKMT2AMEN1LMNA | |
| SCHEMBL7958244 | 0.78 | ELANE (0.57) | ESR2ELANEKMT2AMEN1LMNA | |
| SCHEMBL7961868 | 0.75 | ELANE (0.51) | ESR2ELANEHPGDKMT2AMEN1 | |
| SCHEMBL7960312 | 0.74 | ELANE (0.50) | ESR2ELANEHPGDKMT2AMEN1 | |
| SCHEMBL14177146 | 0.74 | ESR1 (0.76) | ESR1ESR2HPGDKMT2AMEN1 | |
| SCHEMBL7968663 | 0.72 | TTR (0.53) | ELANEKMT2AMEN1LMNARAB9A | |
| SCHEMBL8036021 | 0.72 | ESR1 (0.56) | ESR1ESR2HPGDTYRDAO | |
| SCHEMBL6026933 | 0.72 | ELANE (0.68) | ELANEKMT2AMEN1LMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6184245-B1 | Cyclic ketone derivatives and their medical applications | TORAY INDUSTRIES INC. (JP) | 2001-02-06 | — | — | US | disclosed |