Salicyladehyde

Salicyladehyde

SCHEMBL7961894

COc1nccnc1NN.O=Cc1ccccc1O

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRIM24 O15164 2/20 0.47
TRIM33 Q9UPN9 2/20 0.47
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
HTT P42858 5/20 0.41
KDM4E B2RXH2 4/20 0.41
SMN1; SMN2 Q16637 4/20 0.41
KMT2A Q03164 3/20 0.41
LMNA P02545 1/20 0.41
POLB P06746 1/20 0.41
MEN1 O00255 1/20 0.39
DHFR P00374 1/20 0.38
ERN1 O75460 5/20 0.37
TYR P14679 1/20 0.37
TLR2 O60603 1/20 0.37
TLR1 Q15399 1/20 0.37
TLR6 Q9Y2C9 1/20 0.37
RAB9A P51151 5/20 0.36
PKM P14618 3/20 0.36
GAA P10253 3/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7951745 0.80 ERN1 (0.41) HTTKDM4ESMN1; SMN2KMT2ALMNA
SCHEMBL943566 0.76 MEN1 (0.47) KDM4ESMN1; SMN2KMT2ALMNAMEN1
Salicyladehyde SCHEMBL29000458 0.76 TRIM24 (0.50) TRIM24TRIM33HTTKDM4ESMN1; SMN2
SCHEMBL7963295 0.75 KMT2A (0.65) HTTKDM4ESMN1; SMN2KMT2ALMNA
SCHEMBL7963300 0.75 KMT2A (0.65) HTTKDM4ESMN1; SMN2KMT2ALMNA
Hydrochloric Acid SCHEMBL19552078 0.74 MEN1 (0.46) KDM4ESMN1; SMN2KMT2AMEN1RAB9A
Salicyladehyde SCHEMBL10708393 0.73 TRIM24 (0.82) TRIM24TRIM33CA1CA2HTT
Salicyladehyde SCHEMBL28770773 0.72 TRIM24 (0.56) TRIM24TRIM33HTTKDM4ESMN1; SMN2
Salicyladehyde SCHEMBL28322123 0.72 TRIM24 (0.56) TRIM24TRIM33HTTKDM4ESMN1; SMN2
Salicyladehyde SCHEMBL1980238 0.71 TRIM24 (0.78) TRIM24TRIM33CA1CA2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6329378-B1 HETEROCYCLIC FUNGICIDES AND ANTIGROWTH AGENTS ANADYS PHARMACEUTICALS, INC. 2001-12-11 US claimed
US-6329378-B1 HETEROCYCLIC FUNGICIDES AND ANTIGROWTH AGENTS ANADYS PHARMACEUTICALS, INC. 2001-12-11 US disclosed