Salicyladehyde

Salicyladehyde

SCHEMBL1980238

COOC.O=Cc1ccccc1O

nearest known ligand 0.78

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRIM24 O15164 2/20 0.78
TRIM33 Q9UPN9 2/20 0.78
CA1 P00915 2/20 0.60
CA2 P00918 2/20 0.60
ERN1 O75460 4/20 0.54
LMNA P02545 3/20 0.50
TDP1 Q9NUW8 2/20 0.50
TYR P14679 1/20 0.50
CDK4 P11802 1/20 0.50
CCND1 P24385 1/20 0.50
TLR2 O60603 1/20 0.50
TLR1 Q15399 1/20 0.50
TLR6 Q9Y2C9 1/20 0.50
MEN1 O00255 1/20 0.50
THRB P10828 1/20 0.50
BLM P54132 1/20 0.50
KMT2A Q03164 1/20 0.50
MAPT P10636 2/20 0.47
ALDH1A1 P00352 2/20 0.46
TSHR P16473 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Salicyladehyde SCHEMBL10708393 0.93 TRIM24 (0.82) TRIM24TRIM33CA1CA2ERN1
Salicyladehyde SCHEMBL27610933 0.89 TRIM24 (0.90) TRIM24TRIM33CA1CA2ERN1
Salicyladehyde SCHEMBL10454896 0.89 TRIM24 (0.90) TRIM24TRIM33CA1CA2ERN1
Salicyladehyde SCHEMBL29386538 0.89
Salicyladehyde SCHEMBL901265 0.89 TRIM24 (1.00) TRIM24TRIM33CA1CA2ERN1
Salicyladehyde SCHEMBL15395 0.89
Salicyladehyde SCHEMBL27791581 0.86 TRIM24 (0.86) TRIM24TRIM33CA1CA2ERN1
Salicyladehyde SCHEMBL23628380 0.86 TRIM24 (0.95) TRIM24TRIM33CA1CA2ERN1
Salicyladehyde SCHEMBL5121332 0.86 TRIM24 (0.95) TRIM24TRIM33CA1CA2ERN1
Salicyladehyde SCHEMBL1176891 0.86 TRIM24 (0.95) TRIM24TRIM33CA1CA2ERN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9925153-B2 Therapeutic agents for skin diseases and conditions STC.UNM (US) 2018-03-27 US disclosed
US-20160287531-A1 THERAPEUTIC AGENTS FOR SKIN DISEASES AND CONDITIONS STC.UNM 2016-10-06 US disclosed
WO-2015085143-A2 THERAPEUTIC AGENTS FOR SKIN DISEASES AND CONDITIONS STC.UNM (US) 2015-06-11 WO disclosed
US-8980954-B2 Substituted cis- and trans-stilbenes as therapeutic agents STC.UNM (US) 2015-03-17 US disclosed
US-8524782-B2 Key intermediate for the preparation of Stilbenes, solid forms of Pterostilbene, and methods for making the same LAURUS LABS PRIVATE LIMITED (IN) 2013-09-03 US disclosed
US-20130178536-A1 SUBSTITUTED CIS- AND TRANS-STILBENES AS THERAPEUTIC AGENTS STC.UNM (US) 2013-07-11 US disclosed
US-20110144212-A1 KEY INTERMEDIATE FOR THE PREPARATION OF STILBENES, SOLID FORMS OF PTEROSTILBENE, AND METHODS FOR MAKING THE SAME APTUIT LAURUS PRIVATE LIMITED (IN) 2011-06-16 US disclosed
WO-2010010578-A2 A KEY INTERMEDIATE FOR THE PREPARATION OF STILBENES APTUIT LAURUS PRIVATE LIMITED (IN) 2010-01-28 WO disclosed
US-20070249647-A1 Substituted CIS- and trans-stilbenes as therapeutic agents REGENTS OF THE UNIVERSITY OF NEW MEXICO 2007-10-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160287531-A1 THERAPEUTIC AGENTS FOR SKIN DISEASES AND CONDITIONS CUTA, TSLP, ELANE TRIM24 3780/4885TRIM33 967/4885CA1 4268/4885
US-20070249647-A1 Substituted CIS- and trans-stilbenes as therapeutic agents TGFB1, VHL, TMSB10 TRIM24 3519/4885TRIM33 2507/4885CA1 1178/4885
US-20130178536-A1 SUBSTITUTED CIS- AND TRANS-STILBENES AS THERAPEUTIC AGENTS PSEN1, TERT, PSEN2 TRIM24 2985/4885TRIM33 1844/4885CA1 247/4885
US-20110144212-A1 KEY INTERMEDIATE FOR THE PREPARATION OF STILBENES, SOLID FORMS OF PTEROSTILBENE, AND METHODS FOR MAKING THE SAME SIRT5, SQLE, PDHB TRIM24 2618/4885TRIM33 653/4885CA1 4653/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.