Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 8/20 | 0.52 |
| ▸ | MAPT | P10636 | 8/20 | 0.51 |
| ▸ | HTT | P42858 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | PKM | P14618 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | KLF5 | Q13887 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.51 |
| ▸ | RELA | Q04206 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7962045 | 1.00 | ERN1 (0.52) | ERN1MAPTHTTKDM4EPKM | |
| SCHEMBL7961882 | 0.77 | SMN1; SMN2 (0.53) | MAPTHTTKDM4EPKML3MBTL1 | |
| SCHEMBL7961879 | 0.77 | SMN1; SMN2 (0.53) | MAPTHTTKDM4EPKML3MBTL1 | |
| SCHEMBL7961924 | 0.76 | AMY1A (0.51) | ERN1MAPTHTTKDM4EPKM | |
| SCHEMBL7961922 | 0.76 | AMY1A (0.51) | ERN1MAPTHTTKDM4EPKM | |
| SCHEMBL7960932 | 0.75 | MAPT (0.52) | MAPTHTTKDM4EPKML3MBTL1 | |
| SCHEMBL7960927 | 0.75 | MAPT (0.52) | MAPTHTTKDM4EPKML3MBTL1 | |
| SCHEMBL7963239 | 0.74 | HTT (0.64) | MAPTHTTKDM4EPKML3MBTL1 | |
| SCHEMBL7963233 | 0.74 | HTT (0.64) | MAPTHTTKDM4EPKML3MBTL1 | |
| SCHEMBL7961929 | 0.74 | KMT2A (0.67) | MAPTHTTKDM4EPKML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6329378-B1 | HETEROCYCLIC FUNGICIDES AND ANTIGROWTH AGENTS | ANADYS PHARMACEUTICALS, INC. | 2001-12-11 | — | — | US | claimed |
| US-6329378-B1 | HETEROCYCLIC FUNGICIDES AND ANTIGROWTH AGENTS | ANADYS PHARMACEUTICALS, INC. | 2001-12-11 | — | — | US | disclosed |