Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 20/20 | 0.50 |
| ▸ | PDE4B | Q07343 | 20/20 | 0.50 |
| ▸ | PDE4C | Q08493 | 20/20 | 0.50 |
| ▸ | PDE4D | Q08499 | 20/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1817928 | 0.88 | PDE4B (0.47) | PDE4APDE4BPDE4CPDE4D | |
| Hydrochloric Acid SCHEMBL4282932 | 0.87 | PDE4B (0.48) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL2466398 | 0.87 | PDE4B (0.48) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL6672381 | 0.86 | PDE4B (0.48) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL6155742 | 0.85 | PDE4A (0.53) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL6672386 | 0.85 | PDE4A (0.58) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL6675072 | 0.84 | PDE4B (0.51) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7382150 | 0.83 | PDE4B (0.45) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL3624665 | 0.81 | PDE4B (0.46) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL6672646 | 0.80 | PDE4A (0.52) | PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211367-B1 | REACTING AN 2-IMIDAZOLINE COMPOUND WITH A BENZALDEHYDE; REDUCTION | EURO-CELTIQUE, S.A. (LU) | 2001-04-03 | — | — | US | disclosed |