SCHEMBL3624665

SCHEMBL3624665

CCCc1nc2[c]ncn(Cc3ccc(OC)c(OC4CCCC4)c3)c-2n1

nearest known ligand 0.46

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
PDE4B Q07343 19/20 0.46
PDE4A P27815 18/20 0.46
PDE4C Q08493 18/20 0.46
PDE4D Q08499 18/20 0.46
SSTR5 P35346 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3624661 0.85 PDE4B (0.49) PDE4BPDE4APDE4CPDE4DSSTR5
SCHEMBL7962091 0.81 PDE4A (0.50) PDE4BPDE4APDE4CPDE4D
SCHEMBL1817928 0.79 PDE4B (0.47) PDE4BPDE4APDE4CPDE4D
SCHEMBL2466398 0.79 PDE4B (0.48) PDE4BPDE4APDE4CPDE4D
Hydrochloric Acid SCHEMBL4282932 0.79 PDE4B (0.48) PDE4BPDE4APDE4CPDE4D
SCHEMBL7382150 0.75 PDE4B (0.45) PDE4BPDE4APDE4CPDE4D
SCHEMBL1388089 0.70 PDE4B (0.47) PDE4BPDE4APDE4CPDE4D
SCHEMBL7861139 0.70 PDE4A (0.48) PDE4BPDE4APDE4CPDE4D
Hydrochloric Acid SCHEMBL7862248 0.70 PDE4A (0.47) PDE4BPDE4APDE4CPDE4D
Hydrochloric Acid SCHEMBL6154633 0.70 PDE4B (0.48) PDE4BPDE4APDE4CPDE4D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-4532115-B2 2010-08-25 JP claimed
EP-1463493-A1 METHODS OF INDUCING OVULATION-USING A NON-POLYPEPTIDE CAMP LEVEL MODULATOR Applied Research Systems ARS Holding N.V. (AN) 2004-10-06 EP claimed
WO-2003051344-A1 METHODS OF INDUCING OVULATION_USING A NON-POLYPEPTIDE CAMP LEVEL MODULATOR APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) 2003-06-26 WO claimed
EP-1908463-A2 Methods of inducing ovulation using a non-polypeptide camp level modulator Laboratoires Serono SA (CH) 2008-04-09 EP disclosed