Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 20/20 | 0.61 |
| ▸ | PDE4B | Q07343 | 20/20 | 0.61 |
| ▸ | PDE4C | Q08493 | 20/20 | 0.61 |
| ▸ | PDE4D | Q08499 | 20/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6672384 | 0.86 | PDE4A (0.55) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL6155745 | 0.85 | PDE4A (0.79) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL6672389 | 0.84 | PDE4A (0.81) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL6675074 | 0.82 | PDE4B (0.57) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL6672649 | 0.79 | PDE4A (0.66) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL6672888 | 0.79 | PDE4A (0.62) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7740525 | 0.79 | PDE4A (0.61) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL6674257 | 0.79 | PDE4A (0.61) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL29354661 | 0.76 | PDE4A (1.00) | PDE4APDE4BPDE4CPDE4D | |
| Hydrochloric Acid SCHEMBL29721014 | 0.75 | PDE4A (0.98) | PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211367-B1 | REACTING AN 2-IMIDAZOLINE COMPOUND WITH A BENZALDEHYDE; REDUCTION | EURO-CELTIQUE, S.A. (LU) | 2001-04-03 | — | — | US | disclosed |