Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7955596 | 0.91 | BACE1 (0.72) | CTSDBACE1 | |
| SCHEMBL7963431 | 0.91 | BACE1 (0.72) | CTSDBACE1 | |
| SCHEMBL7957759 | 0.91 | BACE1 (0.72) | CTSDBACE1 | |
| SCHEMBL7960748 | 0.90 | CTSD (0.55) | CTSDBACE1 | |
| SCHEMBL7958539 | 0.90 | CTSD (0.55) | CTSDBACE1 | |
| SCHEMBL12245339 | 0.90 | CTSD (0.55) | CTSDBACE1 | |
| SCHEMBL7961827 | 0.88 | BACE1 (0.64) | CTSDBACE1 | |
| SCHEMBL7954514 | 0.88 | BACE1 (0.64) | CTSDBACE1 | |
| SCHEMBL7958914 | 0.88 | CTSD (0.55) | CTSDBACE1 | |
| SCHEMBL7947077 | 0.88 | CTSD (0.55) | CTSDBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010021680-A2 | INHIBITORS OF BETA-SECRETASE | VITAE PHARMACEUTICALS, INC. (US) | 2010-02-25 | — | — | WO | disclosed |