Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | TK1 | P04183 | 6/20 | 0.35 |
| ▸ | TYMP | P19971 | 3/20 | 0.35 |
| ▸ | TK2 | O00142 | 6/20 | 0.34 |
| ▸ | DUT | P33316 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7962132 | 1.00 | MEN1 (0.46) | MEN1KMT2AHSP90AA1KIF11TK1 | |
| SCHEMBL7147937 | 0.75 | MEN1 (0.41) | MEN1KMT2AHSP90AA1KIF11TK1 | |
| SCHEMBL260261 | 0.74 | HSP90AA1 (0.43) | MEN1KMT2AHSP90AA1KIF11TK1 | |
| SCHEMBL6757289 | 0.71 | HSP90AA1 (0.41) | MEN1KMT2AHSP90AA1KIF11TK1 | |
| SCHEMBL15610884 | 0.70 | SMYD2 (0.42) | DUT | |
| SCHEMBL7961627 | 0.70 | KDM4E (0.43) | MEN1KMT2AHSP90AA1KIF11TK1 | |
| SCHEMBL981247 | 0.69 | — | — | |
| SCHEMBL7963957 | 0.68 | TK2 (0.39) | MEN1KMT2AHSP90AA1KIF11TK1 | |
| SCHEMBL5633963 | 0.68 | MEN1 (0.40) | MEN1KMT2AHSP90AA1KIF11TK1 | |
| SCHEMBL2207347 | 0.68 | MEN1 (0.40) | MEN1KMT2AHSP90AA1KIF11TK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6255339-B1 | PREVENTION PROSGESTERONE RECEPTOR BINDING | MEIJI SEIKA KAISHA, LTD. (JP) | 2001-07-03 | — | — | US | disclosed |
| EP-0885893-A1 | NOVEL TETRAHYDRONAPHTHOFURANONE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | MEIJI SEIKA KAISHA LTD. (JP) | 1998-12-23 | — | — | EP | disclosed |