Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK2 | O00142 | 7/20 | 0.39 |
| ▸ | TK1 | P04183 | 7/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TYMP | P19971 | 4/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7961627 | 0.78 | KDM4E (0.43) | TK2TK1KIF11MEN1KMT2A | |
| SCHEMBL260261 | 0.73 | HSP90AA1 (0.43) | TK2TK1KIF11MEN1KMT2A | |
| SCHEMBL5773507 | 0.70 | MEN1 (0.40) | TK2TK1KIF11MEN1KMT2A | |
| SCHEMBL7152191 | 0.70 | MEN1 (0.38) | TK2TK1KIF11MEN1KMT2A | |
| SCHEMBL7152512 | 0.70 | MEN1 (0.38) | TK2TK1KIF11MEN1KMT2A | |
| SCHEMBL7962135 | 0.68 | MEN1 (0.46) | TK2TK1KIF11MEN1KMT2A | |
| SCHEMBL7962132 | 0.68 | MEN1 (0.46) | TK2TK1KIF11MEN1KMT2A | |
| SCHEMBL7156228 | 0.67 | CYP3A4 (0.37) | TK2TK1KIF11MEN1KMT2A | |
| SCHEMBL14168437 | 0.67 | GRM2 (0.45) | TK2TK1 | |
| SCHEMBL5633963 | 0.67 | MEN1 (0.40) | TK2TK1KIF11MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6255339-B1 | PREVENTION PROSGESTERONE RECEPTOR BINDING | MEIJI SEIKA KAISHA, LTD. (JP) | 2001-07-03 | — | — | US | disclosed |
| EP-0885893-A1 | NOVEL TETRAHYDRONAPHTHOFURANONE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | MEIJI SEIKA KAISHA LTD. (JP) | 1998-12-23 | — | — | EP | disclosed |