Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 7/20 | 0.70 |
| ▸ | NOS3 | P29474 | 6/20 | 0.70 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.60 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.60 |
| ▸ | HTR1A | P08908 | 1/20 | 0.51 |
| ▸ | DRD2 | P14416 | 1/20 | 0.51 |
| ▸ | HTR2A | P28223 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.41 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.39 |
| ▸ | TUBB | P07437 | 1/20 | 0.39 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.39 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.39 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.39 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.39 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.39 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.39 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6618905 | 0.86 | NOS1 (0.67) | NOS1NOS3CHRM2CHRM4HTR1A | |
| SCHEMBL6622654 | 0.83 | NOS1 (0.63) | NOS1NOS3CHRM2CHRM4HTR1A | |
| SCHEMBL6622079 | 0.83 | NOS1 (0.78) | NOS1NOS3CHRM2CHRM4HTR1A | |
| SCHEMBL6617467 | 0.82 | NOS1 (1.00) | NOS1NOS3CHRM2CHRM4HTR1A | |
| SCHEMBL6619070 | 0.82 | NOS1 (0.79) | NOS1NOS3CHRM2CHRM4HTR1A | |
| SCHEMBL7962225 | 0.82 | NOS1 (0.72) | NOS1NOS3CHRM2CHRM4HTR1A | |
| SCHEMBL6620648 | 0.82 | NOS1 (0.73) | NOS1NOS3CHRM2CHRM4HTR1A | |
| SCHEMBL6620491 | 0.81 | NOS1 (0.85) | NOS1NOS3CHRM2CHRM4HTR1A | |
| SCHEMBL6618617 | 0.81 | NOS1 (0.85) | NOS1NOS3CHRM2CHRM4HTR1A | |
| SCHEMBL6617714 | 0.81 | NOS1 (0.70) | NOS1NOS3CHRM2CHRM4HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235747-B1 | NITRIC OXIDE SYNTHASE INHIBITOR | PFIZER INC. | 2001-05-22 | — | — | US | disclosed |