Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 10/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | TNIK | Q9UKE5 | 5/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7959593 | 0.70 | EGFR (0.51) | EGFRFGFR4PIK3CDPIK3CA | |
| SCHEMBL3393275 | 0.70 | EGFR (0.55) | EGFRFGFR4PIK3CDPIK3CATDO2 | |
| SCHEMBL30853054 | 0.70 | EGFR (0.55) | EGFRFGFR4PIK3CDPIK3CATDO2 | |
| SCHEMBL30618089 | 0.70 | EGFR (0.55) | EGFRFGFR4PIK3CDPIK3CATDO2 | |
| SCHEMBL737948 | 0.70 | EGFR (0.55) | EGFRARFGFR4PIK3CDPIK3CA | |
| SCHEMBL2011007 | 0.70 | EGFR (0.55) | EGFRARFGFR4PIK3CDPIK3CA | |
| SCHEMBL5077890 | 0.69 | EGFR (0.51) | EGFRFGFR4PIK3CDPIK3CA | |
| SCHEMBL7962439 | 0.68 | EGFR (0.43) | EGFRARFGFR4PIK3CDPIK3CA | |
| Hydrochloric Acid SCHEMBL30376208 | 0.68 | EGFR (0.53) | EGFRFGFR4PIK3CDPIK3CATDO2 | |
| SCHEMBL27788810 | 0.68 | EGFR (0.53) | EGFRFGFR4PIK3CDPIK3CATDO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6284764-B1 | ANTIPROLIFERATIVE AGENT | PFIZER INC. | 2001-09-04 | — | — | US | disclosed |