Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 6/20 | 0.63 |
| ▸ | NPC1 | O15118 | 6/20 | 0.63 |
| ▸ | RAB9A | P51151 | 6/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.63 |
| ▸ | LMNA | P02545 | 4/20 | 0.63 |
| ▸ | MAPT | P10636 | 2/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | PTPRC | P08575 | 4/20 | 0.52 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | ELANE | P08246 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | CDC25B | P30305 | 1/20 | 0.48 |
| ▸ | S100A4 | P26447 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL479017 | 0.98 | NPC1 (0.66) | MAPK1NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL11547344 | 0.93 | NPC1 (0.56) | MAPK1NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL7718941 | 0.88 | NPC1 (0.64) | MAPK1NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL8849638 | 0.83 | S100A4 (0.59) | MAPK1NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL5604805 | 0.82 | NPC1 (0.61) | MAPK1NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL21416409 | 0.82 | S100A4 (0.63) | MAPK1NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL6254969 | 0.80 | NPC1 (0.63) | MAPK1NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL7318179 | 0.80 | NPC1 (0.96) | MAPK1NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL9673967 | 0.80 | NPC1 (0.63) | MAPK1NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL9209968 | 0.79 | NPC1 (0.68) | MAPK1NPC1RAB9ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8921243-B2 | Fabrics comprising a photocatalyst to produce singlet oxygen from ambient oxygen | VENTANA RESEARCH CORPORATION | 2014-12-30 | — | — | US | disclosed |
| US-8921243-B2 | Fabrics comprising a photocatalyst to produce singlet oxygen from ambient oxygen | VENTANA RESEARCH CORPORATION | 2014-12-30 | — | — | US | disclosed |
| US-8481446-B2 | Chemically-resistant coating composition | VENTANA RESEARCH CORPORATION | 2013-07-09 | — | — | US | disclosed |
| US-8481446-B2 | Chemically-resistant coating composition | VENTANA RESEARCH CORPORATION | 2013-07-09 | — | — | US | disclosed |
| US-20120135651-A1 | Fabrics Comprising a Photocatalyst to Produce Singlet Oxygen from Ambient Oxygen | VENTANA RESEARCH CORPORATION | 2012-05-31 | — | — | US | disclosed |
| US-20120135651-A1 | Fabrics Comprising a Photocatalyst to Produce Singlet Oxygen from Ambient Oxygen | VENTANA RESEARCH CORPORATION | 2012-05-31 | — | — | US | disclosed |
| WO-2011142838-A2 | CHEMICALLY-RESISTANT COATING COMPOSITION | LOMBARID JOHN L (US) | 2011-11-17 | — | — | WO | disclosed |
| US-20100279850-A1 | CHEMICALLY-RESISTANT COATING COMPOSITION | VENTANA RESEARCH CORPORATION | 2010-11-04 | — | — | US | disclosed |
| US-20100279850-A1 | CHEMICALLY-RESISTANT COATING COMPOSITION | VENTANA RESEARCH CORPORATION | 2010-11-04 | — | — | US | disclosed |
| WO-2001077095-A2 | DERIVATIVES OF ALPHA-MERCAPTOACETAMIDE | NOVARTIS AG (CH) | 2001-10-18 | — | — | WO | disclosed |
| US-5338875-A | Boron containing intermediates useful in the preparation of carbapenems | MERCK & CO., INC. (US) | 1994-08-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100279850-A1 | CHEMICALLY-RESISTANT COATING COMPOSITION | DNMT1, VCL, DNMT3L | MAPK1 4146/4885NPC1 1763/4885RAB9A 2057/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.