Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 12/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.50 |
| ▸ | MAPT | P10636 | 8/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.50 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.50 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 6/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 8/20 | 0.45 |
| ▸ | MEN1 | O00255 | 6/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6840370 | 0.74 | ALDH1A1 (0.60) | KDM4EALDH1A1MAPTTDP1CHEK1 | |
| SCHEMBL9399636 | 0.73 | KDM4E (0.46) | KDM4EALDH1A1MAPTTDP1CHEK1 | |
| SCHEMBL25243301 | 0.70 | PDE10A (0.46) | KDM4EALDH1A1MAPTTDP1CHEK1 | |
| Iodomethane SCHEMBL9399521 | 0.70 | KDM4E (0.44) | KDM4EALDH1A1MAPTTDP1CHEK1 | |
| SCHEMBL334476 | 0.69 | KDM4E (0.55) | KDM4EALDH1A1MAPTTDP1CHEK1 | |
| SCHEMBL3538954 | 0.69 | KDM4E (0.55) | KDM4EALDH1A1MAPTTDP1CHEK1 | |
| SCHEMBL20674503 | 0.69 | KDM4E (0.55) | KDM4EALDH1A1MAPTTDP1CHEK1 | |
| SCHEMBL23246964 | 0.69 | KDM4E (0.55) | KDM4EALDH1A1MAPTTDP1CHEK1 | |
| SCHEMBL10207538 | 0.69 | KDM4E (0.58) | KDM4EALDH1A1MAPTTDP1CHEK1 | |
| SCHEMBL19288598 | 0.69 | KDM4E (0.55) | KDM4EALDH1A1MAPTTDP1CHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6187928-B1 | TREATING FUNGAL DISEASES | THE ROCKEFELLER UNIVERSITY | 2001-02-13 | — | — | US | disclosed |
| US-6087510-A | Method of use of imidazolium cations | THE ROCKEFELLER UNIVERSITY (US) | 2000-07-11 | — | — | US | disclosed |
| US-5874587-A | FLUORESCENCE | THE ROCKEFELLER UNIVERSITY (US) | 1999-02-23 | — | — | US | disclosed |