Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 4/20 | 0.37 |
| ▸ | PPARG | P37231 | 3/20 | 0.37 |
| ▸ | FABP4 | P15090 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | TACR3 | P29371 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7521850 | 0.84 | PPARA (0.37) | PPARAPPARGFABP4ALDH1A1POLB | |
| SCHEMBL7521639 | 0.83 | PTGIR (0.42) | ADORA1PPARAPPARGSMN1; SMN2ALDH1A1 | |
| SCHEMBL7974210 | 0.81 | ADORA1 (0.41) | ADORA1PPARAPPARGFABP4SMN1; SMN2 | |
| SCHEMBL7528838 | 0.81 | ADORA1 (0.39) | ADORA1FABP4SMN1; SMN2ALDH1A1POLB | |
| SCHEMBL7972424 | 0.79 | PPARA (0.37) | PPARAPPARGFABP4POLBHSD17B10 | |
| SCHEMBL7523413 | 0.78 | ADORA1 (0.39) | ADORA1PPARAPPARGALDH1A1POLB | |
| SCHEMBL7976455 | 0.77 | PPARA (0.36) | ADORA1PPARAPPARGFABP4POLB | |
| SCHEMBL7976492 | 0.76 | ALOX5 (0.38) | ADORA1PPARAPPARGSMN1; SMN2ALDH1A1 | |
| SCHEMBL7526545 | 0.75 | ADORA1 (0.38) | ADORA1FABP4SMN1; SMN2ALDH1A1POLB | |
| SCHEMBL7519017 | 0.75 | PTGIR (0.42) | ALDH1A1POLBHPGDKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6248766-B1 | CARDIOVASCULAR DISORDERS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-06-19 | — | — | US | disclosed |