Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 7/20 | 0.37 |
| ▸ | TBXA2R | P21731 | 4/20 | 0.37 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | BID | P55957 | 4/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.33 |
| ▸ | BCL2L1 | Q07817 | 3/20 | 0.33 |
| ▸ | BAK1 | Q16611 | 3/20 | 0.33 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.33 |
| ▸ | MAOA | P21397 | 2/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | EP300 | Q09472 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7737674 | 0.90 | MAPT (0.35) | PTGIRTBXA2RLOXL2KDM4ELMNA | |
| SCHEMBL24721674 | 0.82 | PSMB5 (0.42) | PTGIRTBXA2RPOLBKDM4EMAOB | |
| SCHEMBL7959954 | 0.78 | MEN1 (0.48) | PTGIRTBXA2RLMNAPPARA | |
| SCHEMBL5239989 | 0.74 | MAOB (0.56) | POLBMAOB | |
| SCHEMBL7949002 | 0.73 | SMN1; SMN2 (0.56) | PTGIRTBXA2RPOLBKDM4EMAPT | |
| SCHEMBL7958811 | 0.73 | MEN1 (0.41) | PTGIRTBXA2RKDM4ELMNATP53 | |
| SCHEMBL7959190 | 0.73 | PTGIR (0.67) | PTGIRTBXA2RPOLBKDM4E | |
| SCHEMBL7960429 | 0.72 | DAO (0.40) | PTGIRTBXA2RPOLBKDM4ELMNA | |
| SCHEMBL11648609 | 0.69 | POLB (0.43) | POLBKDM4EMAPTTSHRMCL1 | |
| SCHEMBL5763492 | 0.69 | MAOB (0.54) | MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1092639-C | Benzene-fused heterocyclic derivative and use thereof | TORAY INDUSTRIES (JP) | 2002-10-16 | — | — | CN | disclosed |
| US-6323235-B1 | CARDIOVASCULAR DISORDERS, ANTIISCHEMIC AGENTS AND ENZYME INHIBITORS | OHTAKE ATSUSHI (JP) | 2001-11-27 | — | — | US | disclosed |
| US-6043264-A | A THROMBOXANE A2 RECEPTOR ANTAGONIST FOR TREATING HYPERTENSION, THROMBOSIS, ISCHEMIC HEART DISEASES, CIRCULATORY DISEASES, ARTERIOSCLEROSIS, PLATELET FUNCTION DISORDER, HYPERLIPIDEMIA, NEPHRITIS OR ASTHMA | TORAY INDUSTRIES, INC. (JP) | 2000-03-28 | — | — | US | disclosed |
| CN-1148381-A | Benzene-fused heterocyclic derivative and use thereof | TORAY INDUSTRIES (JP) | 1997-04-23 | — | — | CN | disclosed |
| EP-0751126-A1 | BENZENE-FUSED HETEROCYCLIC DERIVATIVE AND USE OF THE SAME | TORAY INDUSTRIES, INC. (JP) | 1997-01-02 | — | — | EP | disclosed |