Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | PTGIR | P43119 | 7/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 4/20 | 0.36 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.34 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7958811 | 0.87 | MEN1 (0.41) | DAOKDM4ETSHRLMNATP53 | |
| SCHEMBL7956750 | 0.79 | PTGIR (0.61) | KDM4ETDP1ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL7958890 | 0.75 | PSMB8 (0.43) | L3MBTL1TDP1ALDH1A1LMNAPTGIR | |
| SCHEMBL7737674 | 0.75 | MAPT (0.35) | KDM4ETSHRTDP1LMNATP53 | |
| SCHEMBL7956749 | 0.74 | PTGIR (0.57) | KDM4ETDP1ALDH1A1POLBPTGIR | |
| SCHEMBL7960638 | 0.73 | TBXA2R (0.30) | PTGIRTBXA2R | |
| SCHEMBL7962816 | 0.72 | PTGIR (0.37) | KDM4ETSHRLMNATP53POLB | |
| SCHEMBL7949002 | 0.69 | SMN1; SMN2 (0.56) | KDM4EL3MBTL1TDP1ALDH1A1POLB | |
| SCHEMBL4003505 | 0.67 | KEAP1 (0.59) | L3MBTL1TSHRTDP1BCL2L1 | |
| 1-Naphthol SCHEMBL9673700 | 0.66 | CYP1A2 (0.63) | DAOKDM4EL3MBTL1TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6323235-B1 | CARDIOVASCULAR DISORDERS, ANTIISCHEMIC AGENTS AND ENZYME INHIBITORS | OHTAKE ATSUSHI (JP) | 2001-11-27 | — | — | US | disclosed |
| US-6043264-A | A THROMBOXANE A2 RECEPTOR ANTAGONIST FOR TREATING HYPERTENSION, THROMBOSIS, ISCHEMIC HEART DISEASES, CIRCULATORY DISEASES, ARTERIOSCLEROSIS, PLATELET FUNCTION DISORDER, HYPERLIPIDEMIA, NEPHRITIS OR ASTHMA | TORAY INDUSTRIES, INC. (JP) | 2000-03-28 | — | — | US | disclosed |
| EP-0751126-A1 | BENZENE-FUSED HETEROCYCLIC DERIVATIVE AND USE OF THE SAME | TORAY INDUSTRIES, INC. (JP) | 1997-01-02 | — | — | EP | disclosed |