SCHEMBL7962890

SCHEMBL7962890

CN1CCCC(CCCn2c(COc3ccc(Cl)cc3)c(CN3CCCCC3)c3ccccc32)C1

nearest known ligand 0.65

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
NPY1R P25929 20/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7949205 0.87 NPY1R (0.67) NPY1R
Hydrochloric Acid SCHEMBL7960370 0.81 NPY1R (0.69) NPY1R
SCHEMBL7960391 0.80 NPY1R (0.60) NPY1R
SCHEMBL7956883 0.79 NPY1R (0.78) NPY1R
SCHEMBL7963501 0.79 NPY1R (1.00) NPY1R
SCHEMBL7963425 0.79 NPY1R (1.00) NPY1R
Hydrochloric Acid SCHEMBL7956797 0.78 NPY1R (0.98) NPY1R
Hydrochloric Acid SCHEMBL7958491 0.77 NPY1R (0.96) NPY1R
SCHEMBL7959869 0.76 NPY1R (0.82) NPY1R
SCHEMBL7959455 0.76 NPY1R (0.50) NPY1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6245761-B1 NERVOUS SYSTEM, CARDIOVASCULAR AND RESPIRATORY SYSTEM DISORDERS ELI LILLY AND COMPANY 2001-06-12 US disclosed
EP-0789688-A4 INDOLYL NEUROPEPTIDE Y RECEPTOR ANTAGONISTS LILLY CO ELI (US) 1997-11-19 EP disclosed
EP-0789688-A1 INDOLYL NEUROPEPTIDE Y RECEPTOR ANTAGONISTS ELI LILLY AND COMPANY (US) 1997-08-20 EP disclosed
WO-1997009308-A1 INDOLYL NEUROPEPTIDE Y RECEPTOR ANTAGONISTS ELI LILLY AND COMPANY (US) 1997-03-13 WO disclosed