SCHEMBL7963501

SCHEMBL7963501

Clc1ccc(OCc2c(CN3CCC(N4CCCCC4)CC3)c3ccccc3n2CCN2CCCCC2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
NPY1R P25929 16/20 1.00
HRH3 Q9Y5N1 3/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7959869 0.90 NPY1R (0.82) NPY1RHRH3
SCHEMBL7960817 0.90 NPY1R (0.82) NPY1RHRH3
SCHEMBL7958627 0.88 NPY1R (1.00) NPY1RHRH3
SCHEMBL7956883 0.88 NPY1R (0.78) NPY1R
Hydrochloric Acid SCHEMBL7960370 0.82 NPY1R (0.69) NPY1R
SCHEMBL7959587 0.82 NPY1R (0.80) NPY1RHRH3
SCHEMBL7959225 0.81 NPY1R (1.00) NPY1RHRH3
SCHEMBL7958759 0.80 NPY1R (0.86) NPY1RHRH3
SCHEMBL7963425 0.79 NPY1R (1.00) NPY1RHRH3
SCHEMBL7962890 0.79 NPY1R (0.65) NPY1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6245761-B1 NERVOUS SYSTEM, CARDIOVASCULAR AND RESPIRATORY SYSTEM DISORDERS ELI LILLY AND COMPANY 2001-06-12 US disclosed
CN-1173867-A Indolyl neuropeptide Y receptor antagonists LILLY CO ELI (US) 1998-02-18 CN disclosed