SCHEMBL7962908

SCHEMBL7962908

CCc1c(C(=O)O)ccnc1-c1cc(C(=O)O)ccn1

nearest known ligand 0.50

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KDM4C Q9H3R0 12/20 0.50
KDM2B Q8NHM5 4/20 0.50
KDM5C P41229 6/20 0.49
KDM4E B2RXH2 4/20 0.49
KDM2A Q9Y2K7 4/20 0.49
KDM3A Q9Y4C1 4/20 0.49
KDM6B O15054 3/20 0.49
KDM5B Q9UGL1 7/20 0.48
KDM5A P29375 4/20 0.48
KDM4A O75164 6/20 0.48
JMJD6 Q6NYC1 1/20 0.47
P4HA1 P13674 1/20 0.47
KDM4B O94953 3/20 0.45
KMO O15229 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7965043 0.82 KDM4C (0.51) KDM4CKDM2BKDM5CKDM4EKDM2A
SCHEMBL7952527 0.81 KDM4C (0.53) KDM4CKDM2BKDM5CKDM4EKDM2A
SCHEMBL528803 0.79 KDM4C (0.53) KDM4CKDM2BKDM5CKDM4EKDM2A
SCHEMBL17220133 0.78 KDM4C (0.51) KDM4CKDM2BKDM5CKDM4EKDM2A
SCHEMBL10526279 0.77 KDM4C (0.49) KDM4CKDM2BKDM5CKDM4EKDM2A
SCHEMBL27541388 0.76 KDM4E (0.44) KDM4CKDM4EKDM5BKDM5AKDM4A
SCHEMBL730406 0.75 KDM4C (0.49) KDM4CKDM2BKDM5CKDM4EKDM2A
SCHEMBL70700 0.74 KDM4C (0.78) KDM4CKDM2BKDM5CKDM4EKDM2A
SCHEMBL29407015 0.74 KDM4C (0.78) KDM4CKDM2BKDM5CKDM4EKDM2A
SCHEMBL23303939 0.72 KMO (0.67) KDM4CKDM2BKDM5CKDM4EKDM2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6187928-B1 TREATING FUNGAL DISEASES THE ROCKEFELLER UNIVERSITY 2001-02-13 US disclosed
US-6087510-A Method of use of imidazolium cations THE ROCKEFELLER UNIVERSITY (US) 2000-07-11 US disclosed
US-5969150-A FLUORESCENT COMPOUNDS FOR MEDICAL DIAGNOSIS, DRUGS AND LABELS OR FUNGICIDES AND VIRICIDES THE ROCKEFELLER UNIVERSITY (US) 1999-10-19 US disclosed
US-5874587-A FLUORESCENCE THE ROCKEFELLER UNIVERSITY (US) 1999-02-23 US disclosed