Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | PGD | P52209 | 1/20 | 0.33 |
| ▸ | PRKCA | P17252 | 1/20 | 0.30 |
| ▸ | MME | P08473 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1521221 | 0.78 | PDE4A (0.39) | PDE4ATSHROR51E2CYP2C9PGD | |
| SCHEMBL7952614 | 0.76 | PDE4A (0.38) | PDE4ATSHROR51E2CYP2C9PGD | |
| SCHEMBL10386577 | 0.75 | PDE4A (0.40) | PDE4ATSHROR51E2TP53CYP2C9 | |
| SCHEMBL10386274 | 0.74 | PDE4A (0.43) | PDE4ATSHROR51E2TP53CYP2C9 | |
| SCHEMBL12672374 | 0.74 | PDE4A (0.43) | PDE4ATSHROR51E2TP53CYP2C9 | |
| SCHEMBL7953367 | 0.73 | MAPT (0.41) | PDE4ATSHROR51E2PRKCAALDH1A1 | |
| SCHEMBL7209363 | 0.72 | TSHR (0.39) | TSHRTP53PGD | |
| SCHEMBL13359066 | 0.72 | TDP1 (0.36) | TSHROR51E2PRKCA | |
| SCHEMBL9806490 | 0.71 | PDE4A (0.40) | PDE4ATSHROR51E2TP53CYP2C9 | |
| SCHEMBL3372433 | 0.70 | PDE4A (0.43) | PDE4ATSHROR51E2CYP2C9PGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6215016-B1 | HEMATOPOIETIC AGENTS; PREVENTING CYTOPENIA | TORAY INDUSTRIES, INC. (JP) | 2001-04-10 | — | — | US | disclosed |
| EP-0841063-A1 | KETONE DERIVATIVES AND MEDICINAL USE THEREOF | TORAY INDUSTRIES, INC. (JP) | 1998-05-13 | — | — | EP | disclosed |