Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 11/20 | 0.59 |
| ▸ | TBXA2R | P21731 | 8/20 | 0.59 |
| ▸ | PSMB5 | P28074 | 4/20 | 0.34 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7963256 | 0.87 | PTGIR (0.67) | PTGIRTBXA2RPSMB5PSMB8KMT2A | |
| SCHEMBL7962535 | 0.86 | PTGIR (0.80) | PTGIRTBXA2RPSMB5PSMB8HPGD | |
| SCHEMBL7958505 | 0.75 | PTGIR (1.00) | PTGIRTBXA2RPSMB5PSMB8HPGD | |
| SCHEMBL7962878 | 0.69 | PTGIR (1.00) | PTGIRTBXA2RPSMB5PSMB8HPGD | |
| SCHEMBL7948621 | 0.69 | PTGIR (0.86) | PTGIRTBXA2RPSMB5PSMB8HPGD | |
| SCHEMBL7958040 | 0.69 | PTGIR (0.86) | PTGIRTBXA2RHPGDKDM4E | |
| SCHEMBL7958576 | 0.69 | PTGIR (0.81) | PTGIRTBXA2RPSMB5PSMB8KDM4E | |
| SCHEMBL7956621 | 0.68 | PTGIR (0.85) | PTGIRTBXA2RMAPTHPGDKDM4E | |
| SCHEMBL7959451 | 0.65 | PTGIR (1.00) | PTGIRTBXA2RPSMB5PSMB8HPGD | |
| SCHEMBL7958337 | 0.64 | PTGIR (1.00) | PTGIRTBXA2RPSMB5PSMB8HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6323235-B1 | CARDIOVASCULAR DISORDERS, ANTIISCHEMIC AGENTS AND ENZYME INHIBITORS | OHTAKE ATSUSHI (JP) | 2001-11-27 | — | — | US | disclosed |
| US-6043264-A | A THROMBOXANE A2 RECEPTOR ANTAGONIST FOR TREATING HYPERTENSION, THROMBOSIS, ISCHEMIC HEART DISEASES, CIRCULATORY DISEASES, ARTERIOSCLEROSIS, PLATELET FUNCTION DISORDER, HYPERLIPIDEMIA, NEPHRITIS OR ASTHMA | TORAY INDUSTRIES, INC. (JP) | 2000-03-28 | — | — | US | disclosed |
| EP-0751126-A1 | BENZENE-FUSED HETEROCYCLIC DERIVATIVE AND USE OF THE SAME | TORAY INDUSTRIES, INC. (JP) | 1997-01-02 | — | — | EP | disclosed |