Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.60 |
| ▸ | NPC1 | O15118 | 8/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | PKM | P14618 | 4/20 | 0.60 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 6/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.57 |
| ▸ | MEN1 | O00255 | 5/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.56 |
| ▸ | HTT | P42858 | 5/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.53 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.53 |
| ▸ | RELA | Q04206 | 2/20 | 0.53 |
| ▸ | KLF5 | Q13887 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 3/20 | 0.53 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7964118 | 1.00 | MAPT (0.60) | MAPTNPC1ALDH1A1PKMRXFP1 | |
| SCHEMBL7951018 | 0.83 | KDM4E (0.60) | MAPTNPC1ALDH1A1PKMRAB9A | |
| SCHEMBL7951013 | 0.83 | KDM4E (0.60) | MAPTNPC1ALDH1A1PKMRAB9A | |
| SCHEMBL7965463 | 0.81 | MAPT (0.58) | MAPTNPC1ALDH1A1PKMRXFP1 | |
| SCHEMBL7965465 | 0.81 | MAPT (0.58) | MAPTNPC1ALDH1A1PKMRXFP1 | |
| SCHEMBL12786519 | 0.78 | ALDH1A1 (0.61) | MAPTNPC1ALDH1A1PKMRXFP1 | |
| SCHEMBL7963239 | 0.78 | HTT (0.64) | MAPTNPC1ALDH1A1PKMRAB9A | |
| SCHEMBL7963233 | 0.78 | HTT (0.64) | MAPTNPC1ALDH1A1PKMRAB9A | |
| SCHEMBL7963295 | 0.78 | KMT2A (0.65) | MAPTNPC1ALDH1A1PKMRAB9A | |
| SCHEMBL7963300 | 0.78 | KMT2A (0.65) | MAPTNPC1ALDH1A1PKMRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6329378-B1 | HETEROCYCLIC FUNGICIDES AND ANTIGROWTH AGENTS | ANADYS PHARMACEUTICALS, INC. | 2001-12-11 | — | — | US | claimed |
| US-6320052-B1 | CRYSTALLINE PRECURSORS OF 1-(((1(R)-(3-(2-(7-CHLORO-2-QUINO LYNYL)ETHENYL)PHENYL)-3-(2-HYDROXY-1-METHYL-ETHYL)PHENYL) PROPYL)THIO)METHYL)CYCLOPROPYLACETIC ACID | MERCK & CO., INC. | 2001-11-20 | — | — | US | claimed |
| US-6329378-B1 | HETEROCYCLIC FUNGICIDES AND ANTIGROWTH AGENTS | ANADYS PHARMACEUTICALS, INC. | 2001-12-11 | — | — | US | disclosed |