Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.64 |
| ▸ | MEN1 | O00255 | 3/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | NQO2 | P16083 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL148001 | 0.85 | MAPT (0.85) | MAPTKMT2AMEN1LMNACYP1A2 | |
| SCHEMBL24452418 | 0.85 | KDM4E (0.54) | MAPTKMT2AMEN1LMNAPOLB | |
| SCHEMBL29539965 | 0.85 | MAPT (0.85) | MAPTKMT2AMEN1LMNACYP1A2 | |
| SCHEMBL7974817 | 0.83 | MAPT (0.68) | MAPTKMT2AMEN1LMNACYP1A2 | |
| SCHEMBL16093634 | 0.80 | MAPT (0.53) | MAPTKMT2AMEN1LMNACYP1A2 | |
| SCHEMBL28710625 | 0.79 | MAPT (0.81) | MAPTKMT2AMEN1LMNACYP1A2 | |
| SCHEMBL29767664 | 0.79 | MAPT (0.81) | MAPTKMT2AMEN1LMNACYP1A2 | |
| SCHEMBL29648254 | 0.79 | MAPT (0.67) | MAPTKMT2AMEN1LMNACYP1A2 | |
| SCHEMBL149167 | 0.78 | MAPT (1.00) | MAPTKMT2AMEN1LMNACYP1A2 | |
| SCHEMBL7963388 | 0.78 | KDM4E (0.58) | MAPTKMT2AMEN1LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001007409-A1 | CARBAZOLE DERIVATIVES AND THEIR USE AS NEUROPEPTIDE Y5 RECEPTOR LIGANDS | ASTRAZENECA UK LIMITED (GB) | 2001-02-01 | — | — | WO | disclosed |