Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 3/20 | 0.43 |
| ▸ | CNR2 | P34972 | 3/20 | 0.43 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CFTR | P13569 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30013273 | 0.88 | MAPT (0.66) | MAPTMEN1KMT2ALMNAPOLB | |
| SCHEMBL9397206 | 0.81 | MAPT (0.79) | MAPTMEN1KMT2ALMNAPOLB | |
| SCHEMBL16093698 | 0.80 | ALDH1A1 (0.58) | MAPTMEN1KMT2ALMNAPOLB | |
| SCHEMBL7963373 | 0.80 | MAPT (0.64) | MAPTMEN1KMT2ALMNAPOLB | |
| SCHEMBL16099561 | 0.79 | KDM4E (0.47) | MAPTMEN1KMT2ALMNAPOLB | |
| SCHEMBL16093752 | 0.79 | HPGD (0.44) | MAPTMEN1KMT2ALMNACNR2 | |
| SCHEMBL16097572 | 0.79 | ALDH1A1 (0.44) | MAPTLMNASIGMAR1 | |
| SCHEMBL16093633 | 0.77 | MAPT (0.54) | MAPTMEN1KMT2ALMNAPOLB | |
| SCHEMBL3039635 | 0.77 | MAPT (0.59) | MAPTMEN1KMT2ALMNAPOLB | |
| SCHEMBL16099757 | 0.76 | PTGER4 (0.54) | MAPTMEN1KMT2APOLBCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014153043-A1 | COMPOUNDS AND METHODS FOR TREATING CANCERS | HEALTH RESEARCH, INC. (US) | 2014-09-25 | — | — | WO | disclosed |