Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CMA1 | P23946 | 9/20 | 0.48 |
| ▸ | CTSG | P08311 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 6/20 | 0.45 |
| ▸ | HTR2C | P28335 | 5/20 | 0.44 |
| ▸ | HTR2B | P41595 | 4/20 | 0.44 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | HTR1D | P28221 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL5265557 | 0.85 | HTR2A (0.57) | CMA1CTSGHTR2AHTR2CHTR2B | |
| SCHEMBL4552632 | 0.84 | CMA1 (0.52) | CMA1CTSGHTR2AHTR2CHTR2B | |
| Ammonia Solution, Strong SCHEMBL27500614 | 0.81 | CMA1 (0.47) | CMA1CTSGHTR2AHTR2CHTR2B | |
| SCHEMBL4572379 | 0.81 | HTR2A (0.48) | CMA1CTSGHTR2AHTR2CHTR2B | |
| SCHEMBL2309552 | 0.79 | CMA1 (0.46) | CMA1CTSGHTR2AHTR2CHTR2B | |
| SCHEMBL8212651 | 0.79 | CMA1 (0.46) | CMA1CTSGHTR2AHTR2CHTR2B | |
| SCHEMBL1093151 | 0.79 | CMA1 (0.46) | CMA1CTSGHTR2AHTR2CHTR2B | |
| SCHEMBL5271283 | 0.79 | HTR2C (0.69) | CMA1CTSGHTR2AHTR2CHTR2B | |
| SCHEMBL4570287 | 0.79 | CMA1 (0.46) | CMA1CTSGHTR2AHTR2CHTR2B | |
| SCHEMBL1856232 | 0.78 | CMA1 (0.45) | CMA1CTSGHTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010019417-A2 | CHYMASE INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-02-18 | — | — | WO | disclosed |