Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 6/20 | 0.64 |
| ▸ | CCR5 | P51681 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | F8 | P00451 | 1/20 | 0.39 |
| ▸ | F5 | P12259 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7957272 | 0.87 | NPY1R (0.70) | NPY1RMAPTKMT2ASMN1; SMN2CYP1A2 | |
| Hydrochloric Acid SCHEMBL7957006 | 0.83 | NPY1R (0.83) | NPY1RMAPTKMT2ASMN1; SMN2CYP1A2 | |
| SCHEMBL7959266 | 0.80 | NPY1R (0.63) | NPY1RMAPTKMT2ASMN1; SMN2CYP1A2 | |
| SCHEMBL7963665 | 0.79 | NPY1R (0.77) | NPY1RMAPTSMN1; SMN2F8F5 | |
| SCHEMBL7959165 | 0.79 | NPY1R (0.75) | NPY1RKDM4ECYP1A2CYP2D6GAA | |
| Hydrochloric Acid SCHEMBL7959693 | 0.77 | NPY1R (0.98) | NPY1RMAPTKMT2ASMN1; SMN2CYP1A2 | |
| Hydrochloric Acid SCHEMBL7957029 | 0.75 | NPY1R (0.69) | NPY1RCCR5GAA | |
| SCHEMBL7959581 | 0.75 | NPY1R (0.68) | NPY1R | |
| Hydrochloric Acid SCHEMBL7949199 | 0.74 | NPY1R (0.59) | NPY1RMAPTKMT2ASMN1; SMN2LMNA | |
| SCHEMBL7959923 | 0.72 | NPY1R (1.00) | NPY1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6245761-B1 | NERVOUS SYSTEM, CARDIOVASCULAR AND RESPIRATORY SYSTEM DISORDERS | ELI LILLY AND COMPANY | 2001-06-12 | — | — | US | disclosed |