Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.34 |
| ▸ | APLNR | P35414 | 1/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | G6PD | P11413 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14296414 | 0.85 | ALDH1A1 (0.63) | ALDH1A1LMNAHTTPPP1CATDP1 | |
| SCHEMBL1555269 | 0.83 | ALDH1A1 (0.61) | ALDH1A1LMNAHTTPPP1CATDP1 | |
| SCHEMBL1555270 | 0.83 | ALDH1A1 (0.61) | ALDH1A1LMNAHTTPPP1CATDP1 | |
| SCHEMBL1555271 | 0.83 | ALDH1A1 (0.61) | ALDH1A1LMNAHTTPPP1CATDP1 | |
| SCHEMBL2024842 | 0.83 | ALDH1A1 (0.61) | ALDH1A1LMNAHTTPPP1CATDP1 | |
| SCHEMBL1840552 | 0.82 | ALDH1A1 (0.50) | ALDH1A1LMNAHTTPPP1CATDP1 | |
| SCHEMBL7963465 | 0.81 | ALDH1A1 (0.59) | ALDH1A1LMNAHTTPPP1CATDP1 | |
| SCHEMBL4228227 | 0.81 | ALDH1A1 (0.58) | ALDH1A1LMNAHTTPPP1CATDP1 | |
| SCHEMBL17728269 | 0.80 | ALDH1A1 (0.54) | ALDH1A1LMNAHTTPPP1CATDP1 | |
| SCHEMBL9343577 | 0.80 | ALDH1A1 (0.58) | ALDH1A1LMNAHTTPPP1CATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001007409-A1 | CARBAZOLE DERIVATIVES AND THEIR USE AS NEUROPEPTIDE Y5 RECEPTOR LIGANDS | ASTRAZENECA UK LIMITED (GB) | 2001-02-01 | — | — | WO | disclosed |