Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | ACKR3 | P25106 | 3/20 | 0.47 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.46 |
| ▸ | FPR3 | P25089 | 1/20 | 0.43 |
| ▸ | FPR2 | P25090 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | POLR1A | O95602 | 1/20 | 0.40 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.39 |
| ▸ | TERT | O14746 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | GLS | O94925 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6395379 | 0.85 | ACKR3 (0.51) | ALDH1A1ACKR3CHRM4FPR3FPR2 | |
| SCHEMBL49464 | 0.85 | ACKR3 (0.51) | ALDH1A1ACKR3CHRM4FPR3FPR2 | |
| SCHEMBL9887516 | 0.83 | ACKR3 (0.50) | ALDH1A1ACKR3CHRM4FPR3FPR2 | |
| SCHEMBL4747740 | 0.83 | ALDH1A1 (0.48) | ALDH1A1ACKR3CHRM4FPR3FPR2 | |
| SCHEMBL424247 | 0.83 | ALDH1A1 (0.48) | ALDH1A1ACKR3CHRM4FPR3FPR2 | |
| SCHEMBL4528736 | 0.83 | ALDH1A1 (0.48) | ALDH1A1ACKR3CHRM4FPR3FPR2 | |
| SCHEMBL12156865 | 0.82 | ACKR3 (0.52) | ALDH1A1ACKR3CHRM4FPR3FPR2 | |
| SCHEMBL23354623 | 0.81 | ALDH1A1 (0.46) | ALDH1A1ACKR3CHRM4FPR3FPR2 | |
| SCHEMBL12788561 | 0.81 | ACKR3 (0.46) | ALDH1A1ACKR3CHRM4FPR3FPR2 | |
| SCHEMBL12155765 | 0.81 | DPP4 (0.46) | ALDH1A1ACKR3CHRM4FPR3FPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001007409-A1 | CARBAZOLE DERIVATIVES AND THEIR USE AS NEUROPEPTIDE Y5 RECEPTOR LIGANDS | ASTRAZENECA UK LIMITED (GB) | 2001-02-01 | — | — | WO | disclosed |