Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 2/20 | 0.53 |
| ▸ | OGG1 | O15527 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.50 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.50 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.45 |
| ▸ | CES1 | P23141 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10187752 | 0.82 | GSK3B (0.55) | GSK3BOGG1HDAC1HDAC8HDAC3 | |
| SCHEMBL7963547 | 0.82 | GSK3B (0.55) | GSK3BOGG1HDAC1HDAC8HDAC3 | |
| SCHEMBL3323642 | 0.81 | GSK3B (0.53) | GSK3BOGG1HDAC1HDAC8HDAC3 | |
| SCHEMBL11155054 | 0.80 | CYP3A4 (0.58) | GSK3BMAPTALDH1A1GAACES1 | |
| SCHEMBL11558787 | 0.79 | HAO1 (0.54) | GSK3BOGG1HDAC1HDAC8HDAC3 | |
| SCHEMBL5640455 | 0.78 | GSK3B (0.50) | GSK3BOGG1HDAC1HDAC8HDAC3 | |
| SCHEMBL12098895 | 0.78 | GSK3B (0.59) | GSK3BOGG1HDAC1HDAC8HDAC3 | |
| SCHEMBL11060497 | 0.78 | OGG1 (0.63) | GSK3BOGG1HDAC1HDAC8HDAC3 | |
| SCHEMBL1305020 | 0.77 | GSK3B (0.70) | GSK3BOGG1HDAC1HDAC8HDAC3 | |
| SCHEMBL21142672 | 0.77 | GSK3B (0.48) | GSK3BOGG1HDAC1HDAC8HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001007409-A1 | CARBAZOLE DERIVATIVES AND THEIR USE AS NEUROPEPTIDE Y5 RECEPTOR LIGANDS | ASTRAZENECA UK LIMITED (GB) | 2001-02-01 | — | — | WO | disclosed |