Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HAAO | P46952 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | SELL | P14151 | 1/20 | 0.40 |
| ▸ | SELP | P16109 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | GABRP | O00591 | 1/20 | 0.38 |
| ▸ | GABRD | O14764 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3073816 | 0.84 | CYP1A2 (0.44) | HAAOCYP1A2ALDH1A1KDM4EHPGD | |
| SCHEMBL6235114 | 0.83 | SIRT3 (0.42) | ALDH1A1KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL11773347 | 0.83 | SIRT3 (0.31) | HAAOHPGDTDP1 | |
| SCHEMBL28649241 | 0.81 | HAAO (0.41) | HAAOCYP1A2ALDH1A1KDM4EHPGD | |
| SCHEMBL11723799 | 0.81 | HAAO (0.41) | HAAOCYP1A2ALDH1A1KDM4EHPGD | |
| SCHEMBL11777515 | 0.81 | SELL (0.54) | HAAOCYP1A2ALDH1A1KDM4EHPGD | |
| SCHEMBL29370019 | 0.79 | CYP1A2 (0.48) | HAAOCYP1A2ALDH1A1KDM4EHPGD | |
| SCHEMBL242262 | 0.79 | CYP1A2 (0.48) | HAAOCYP1A2ALDH1A1KDM4EHPGD | |
| SCHEMBL28033212 | 0.79 | CYP1A2 (0.48) | HAAOCYP1A2ALDH1A1KDM4EHPGD | |
| SCHEMBL11775719 | 0.79 | KDM4E (0.40) | HAAOCYP1A2ALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001034573-A1 | COMPOUNDS | ASTRAZENECA AB (SE) | 2001-05-17 | — | — | WO | disclosed |