Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HAAO | P46952 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.39 |
| ▸ | SELL | P14151 | 1/20 | 0.39 |
| ▸ | SELP | P16109 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CDC25B | P30305 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | GABRP | O00591 | 1/20 | 0.37 |
| ▸ | GABRD | O14764 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23699558 | 0.85 | TDP1 (0.41) | ALDH1A1KDM4EHPGDHSD17B10NOTUM | |
| SCHEMBL28639961 | 0.83 | HAAO (0.41) | HAAOCYP1A2ALDH1A1AKR1C3KDM4E | |
| SCHEMBL3073816 | 0.83 | CYP1A2 (0.44) | HAAOCYP1A2ALDH1A1AKR1C3KDM4E | |
| SCHEMBL7963843 | 0.81 | HAAO (0.42) | HAAOCYP1A2ALDH1A1AKR1C3KDM4E | |
| SCHEMBL605144 | 0.80 | CYP1A2 (0.46) | HAAOCYP1A2ALDH1A1AKR1C3KDM4E | |
| SCHEMBL11777515 | 0.79 | SELL (0.54) | HAAOCYP1A2ALDH1A1KDM4EHPGD | |
| SCHEMBL139141 | 0.78 | CYP1A2 (0.44) | HAAOCYP1A2ALDH1A1AKR1C3KDM4E | |
| SCHEMBL29400914 | 0.78 | CYP1A2 (0.44) | HAAOCYP1A2ALDH1A1AKR1C3KDM4E | |
| SCHEMBL8879082 | 0.78 | CYP1A2 (0.44) | HAAOCYP1A2ALDH1A1AKR1C3KDM4E | |
| SCHEMBL11775719 | 0.78 | KDM4E (0.40) | HAAOCYP1A2ALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4025505-A | ANTICONVULSANTS | CIBA-GEIGY CORPORATION (US) | 1977-05-24 | — | — | US | disclosed |