Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 3/20 | 0.60 |
| ▸ | DRD4 | P21917 | 6/20 | 0.52 |
| ▸ | DRD2 | P14416 | 3/20 | 0.52 |
| ▸ | NPFFR2 | Q9Y5X5 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2433288 | 1.00 | SLC6A4 (0.60) | SLC6A4DRD4DRD2NPFFR2HPGD | |
| SCHEMBL2437393 | 0.84 | SLC6A4 (0.50) | SLC6A4DRD4DRD2NPFFR2HPGD | |
| SCHEMBL2437392 | 0.84 | SLC6A4 (0.50) | SLC6A4DRD4DRD2NPFFR2HPGD | |
| SCHEMBL2432566 | 0.83 | SLC6A4 (0.49) | SLC6A4DRD4DRD2NPFFR2HPGD | |
| SCHEMBL12293338 | 0.83 | SLC6A4 (0.49) | SLC6A4DRD4DRD2NPFFR2HPGD | |
| SCHEMBL2432564 | 0.83 | SLC6A4 (0.49) | SLC6A4DRD4DRD2NPFFR2HPGD | |
| SCHEMBL2432542 | 0.82 | SLC6A4 (0.55) | SLC6A4DRD4DRD2NPFFR2HPGD | |
| SCHEMBL2432539 | 0.82 | SLC6A4 (0.55) | SLC6A4DRD4DRD2NPFFR2HPGD | |
| SCHEMBL7987652 | 0.82 | SLC6A4 (0.50) | SLC6A4NPFFR2 | |
| SCHEMBL20953933 | 0.82 | SLC6A4 (0.48) | SLC6A4DRD4DRD2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010011302-A1 | CERTAIN KYNURENINE-3-MONOOXYGENASE INHIBITORS, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE THEREOF | CHDI, INC. (US) | 2010-01-28 | — | — | WO | disclosed |