Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 3/20 | 0.50 |
| ▸ | NPFFR2 | Q9Y5X5 | 2/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | NPFFR1 | Q9GZQ6 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | PNMT | P11086 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7963848 | 0.82 | SLC6A4 (0.60) | SLC6A4NPFFR2 | |
| SCHEMBL2433288 | 0.82 | SLC6A4 (0.60) | SLC6A4NPFFR2 | |
| SCHEMBL12327098 | 0.73 | TSHR (0.44) | SLC6A4NPFFR2GRIN2BNPFFR1TSHR | |
| SCHEMBL11879954 | 0.69 | TSHR (0.44) | NPFFR2TSHRMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11879950 | 0.69 | TSHR (0.44) | NPFFR2TSHRMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL13778642 | 0.69 | GAA (0.54) | SLC6A4NPFFR2TSHRMEN1KMT2A | |
| SCHEMBL11648028 | 0.68 | SLC6A4 (0.80) | SLC6A4TSHRMEN1KMT2ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL11861782 | 0.68 | TSHR (0.42) | NPFFR2TSHRMEN1KMT2ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL11861777 | 0.68 | TSHR (0.42) | NPFFR2TSHRMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL24404082 | 0.68 | TSHR (0.38) | SLC6A4NPFFR2TSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010011302-A1 | CERTAIN KYNURENINE-3-MONOOXYGENASE INHIBITORS, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE THEREOF | CHDI, INC. (US) | 2010-01-28 | — | — | WO | disclosed |