Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 17/20 | 0.59 |
| ▸ | ADRA1B | P35368 | 15/20 | 0.59 |
| ▸ | ADRA1D | P25100 | 14/20 | 0.59 |
| ▸ | HRH1 | P35367 | 2/20 | 0.59 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.52 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.52 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.52 |
| ▸ | CCR3 | P51677 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7961316 | 1.00 | ADRA1A (0.59) | ADRA1AADRA1BADRA1DHRH1ADRA2A | |
| SCHEMBL7966154 | 1.00 | ADRA1A (0.59) | ADRA1AADRA1BADRA1DHRH1ADRA2A | |
| Hydrochloric Acid SCHEMBL7951346 | 0.99 | ADRA1A (0.58) | ADRA1AADRA1BADRA1DHRH1ADRA2A | |
| Hydrochloric Acid SCHEMBL7954708 | 0.99 | ADRA1A (0.58) | ADRA1AADRA1BADRA1DHRH1ADRA2A | |
| SCHEMBL7951534 | 0.90 | ADRA1A (0.57) | ADRA1AADRA1BADRA1DHRH1ADRA2A | |
| SCHEMBL7962310 | 0.89 | ADRA1A (0.58) | ADRA1AADRA1BADRA1DHRH1ADRA2A | |
| SCHEMBL7962548 | 0.89 | ADRA1A (0.58) | ADRA1AADRA1BADRA1DHRH1ADRA2A | |
| SCHEMBL7951819 | 0.87 | ADRA1A (0.56) | ADRA1AADRA1BADRA1DHRH1ADRA2A | |
| SCHEMBL7966171 | 0.87 | ADRA1A (0.56) | ADRA1AADRA1BADRA1DHRH1ADRA2A | |
| Hydrochloric Acid SCHEMBL7966417 | 0.86 | ADRA1A (0.55) | ADRA1AADRA1BADRA1DHRH1ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6326372-B1 | BENIGN PROSTATE HYPERPLASIA | MERCK & CO., INC. | 2001-12-04 | — | — | US | disclosed |