Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.67 |
| ▸ | MEN1 | O00255 | 2/20 | 0.67 |
| ▸ | UBE2M | P61081 | 7/20 | 0.44 |
| ▸ | DCUN1D1 | Q96GG9 | 7/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7964001 | 1.00 | KMT2A (0.67) | KMT2AMEN1UBE2MDCUN1D1GAA | |
| SCHEMBL7963999 | 1.00 | KMT2A (0.67) | KMT2AMEN1UBE2MDCUN1D1GAA | |
| SCHEMBL16545296 | 0.81 | KMT2A (0.59) | KMT2AMEN1UBE2MDCUN1D1GAA | |
| SCHEMBL2710382 | 0.80 | KMT2A (1.00) | KMT2AMEN1UBE2MDCUN1D1GAA | |
| SCHEMBL5758952 | 0.80 | ALDH1A1 (0.43) | KMT2AMEN1GAAALDH1A1TP53 | |
| SCHEMBL5761670 | 0.80 | ALDH1A1 (0.43) | KMT2AMEN1GAAALDH1A1TP53 | |
| SCHEMBL5761660 | 0.80 | ALDH1A1 (0.43) | KMT2AMEN1GAAALDH1A1TP53 | |
| SCHEMBL5758961 | 0.80 | ALDH1A1 (0.43) | KMT2AMEN1GAAALDH1A1TP53 | |
| SCHEMBL5758956 | 0.80 | ALDH1A1 (0.43) | KMT2AMEN1GAAALDH1A1TP53 | |
| SCHEMBL24819771 | 0.79 | KMT2A (0.57) | KMT2AMEN1UBE2MDCUN1D1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6303627-B1 | FOR THERAPY OF PHYSIOLOGICAL AND PSYCHOLOGICAL DISORDERS | ELI LILLY AND COMPANY | 2001-10-16 | — | — | US | disclosed |
| WO-1999065487-A1 | INHIBITORS OF SEROTONIN REUPTAKE | ELI LILLY AND COMPANY (US) | 1999-12-23 | — | — | WO | disclosed |
| EP-0965587-A1 | Tetrahydropyridinyl- and piperidinyl Inhibitors of serotonin reuptake | ELI LILLY AND COMPANY (US) | 1999-12-22 | — | — | EP | disclosed |