Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 6/20 | 0.54 |
| ▸ | PTGER4 | P35408 | 5/20 | 0.54 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.54 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.51 |
| ▸ | FABP4 | P15090 | 2/20 | 0.33 |
| ▸ | FABP3 | P05413 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 5/20 | 0.33 |
| ▸ | DRD3 | P35462 | 5/20 | 0.33 |
| ▸ | DRD4 | P21917 | 3/20 | 0.33 |
| ▸ | DRD1 | P21728 | 2/20 | 0.33 |
| ▸ | DRD5 | P21918 | 2/20 | 0.33 |
| ▸ | HTR1D | P28221 | 2/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.30 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.30 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.30 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7960041 | 0.92 | PTGER4 (0.56) | PTGIRPTGER4PTGER1PTGER3FABP4 | |
| SCHEMBL7486687 | 0.87 | PTGIR (0.57) | PTGIRPTGER4PTGER1PTGER3FABP4 | |
| SCHEMBL8546529 | 0.86 | PTGIR (0.61) | PTGIRPTGER4PTGER1PTGER3FABP4 | |
| SCHEMBL7959959 | 0.85 | PTGIR (0.59) | PTGIRPTGER4PTGER1PTGER3FABP4 | |
| SCHEMBL7964274 | 0.85 | PTGIR (0.54) | PTGIRPTGER4PTGER1PTGER3FABP4 | |
| SCHEMBL7499969 | 0.84 | PTGIR (0.61) | PTGIRPTGER4PTGER1PTGER3FABP4 | |
| SCHEMBL7960526 | 0.84 | PTGIR (0.60) | PTGIRPTGER4PTGER1PTGER3FABP4 | |
| SCHEMBL8546524 | 0.84 | PTGIR (0.58) | PTGIRPTGER4PTGER1PTGER3FABP4 | |
| SCHEMBL7486495 | 0.83 | PTGIR (0.61) | PTGIRPTGER4PTGER1PTGER3FABP4 | |
| SCHEMBL7949627 | 0.83 | PTGIR (0.69) | PTGIRPTGER4PTGER1PTGER3FABP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6245790-B1 | ANTIINFLAMMATORY AGENTS; GASTROINTESTINAL DISORDERS; SKN DISORDERS; BONE DISORDERS; MUSCLE RELAXANTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-06-12 | — | — | US | disclosed |
| EP-0989975-A1 | OXAZOLE COMPOUNDS USEFUL AS PGE2 AGONISTS AND ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-04-05 | — | — | EP | disclosed |
| WO-2000016760-A2 | NEW USE OF PROSTAGLANDIN E2 ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-03-30 | — | — | WO | disclosed |
| WO-1998055468-A1 | OXAZOLE COMPOUNDS USEFUL AS PGE2 AGONISTS AND ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-12-10 | — | — | WO | disclosed |