Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 9/20 | 0.54 |
| ▸ | PTGER4 | P35408 | 5/20 | 0.54 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.54 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.53 |
| ▸ | PPARA | Q07869 | 3/20 | 0.34 |
| ▸ | PPARD | Q03181 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | FABP4 | P15090 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7489516 | 0.88 | PTGER4 (0.56) | PTGIRPTGER4PTGER1PTGER3PPARD | |
| SCHEMBL7960526 | 0.87 | PTGIR (0.60) | PTGIRPTGER4PTGER1PTGER3KDM4E | |
| SCHEMBL7959959 | 0.87 | PTGIR (0.59) | PTGIRPTGER4PTGER1PTGER3PPARA | |
| SCHEMBL7479528 | 0.87 | PTGIR (0.69) | PTGIRPTGER4PTGER1PTGER3KDM4E | |
| SCHEMBL7479534 | 0.87 | PTGIR (0.69) | PTGIRPTGER4PTGER1PTGER3KDM4E | |
| SCHEMBL7949627 | 0.87 | PTGIR (0.69) | PTGIRPTGER4PTGER1PTGER3KDM4E | |
| SCHEMBL8551042 | 0.87 | PTGIR (0.60) | PTGIRPTGER4PTGER1PTGER3PPARA | |
| SCHEMBL7475683 | 0.86 | PTGIR (0.62) | PTGIRPTGER4PTGER1PTGER3KDM4E | |
| SCHEMBL7949681 | 0.86 | PTGIR (0.58) | PTGIRPTGER4PTGER1PTGER3KDM4E | |
| SCHEMBL7960041 | 0.85 | PTGER4 (0.56) | PTGIRPTGER4PTGER1PTGER3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6245790-B1 | ANTIINFLAMMATORY AGENTS; GASTROINTESTINAL DISORDERS; SKN DISORDERS; BONE DISORDERS; MUSCLE RELAXANTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-06-12 | — | — | US | disclosed |