Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 9/20 | 0.60 |
| ▸ | PTGER4 | P35408 | 5/20 | 0.60 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.60 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | FABP4 | P15090 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8551039 | 0.93 | PTGIR (0.57) | PTGIRPTGER4PTGER1PTGER3KDM4E | |
| SCHEMBL7494436 | 0.90 | PTGIR (0.65) | PTGIRPTGER4PTGER1PTGER3KDM4E | |
| SCHEMBL7489516 | 0.90 | PTGER4 (0.56) | PTGIRPTGER4PTGER1PTGER3KDM4E | |
| SCHEMBL8548332 | 0.88 | PTGIR (0.66) | PTGIRPTGER4PTGER1PTGER3KDM4E | |
| SCHEMBL9006710 | 0.87 | PTGIR (0.75) | PTGIRPTGER4PTGER1PTGER3KDM4E | |
| SCHEMBL8075231 | 0.87 | PTGIR (0.75) | PTGIRPTGER4PTGER1PTGER3KDM4E | |
| SCHEMBL7964459 | 0.87 | PTGER4 (0.73) | PTGIRPTGER4PTGER1PTGER3KDM4E | |
| SCHEMBL7964274 | 0.87 | PTGIR (0.54) | PTGIRPTGER4PTGER1PTGER3KDM4E | |
| SCHEMBL7488841 | 0.86 | PTGER4 (0.61) | PTGIRPTGER4PTGER1PTGER3KDM4E | |
| SCHEMBL8551740 | 0.86 | PTGIR (0.66) | PTGIRPTGER4PTGER1PTGER3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0842161-A1 | 4,5-DIARYL OXAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-05-20 | — | — | EP | disclosed |