Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | IGF1R | P08069 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7958288 | 0.93 | KMT2A (0.42) | KMT2APOLBKDM4EALDH1A1HPGD | |
| SCHEMBL7412623 | 0.92 | IGF1R (0.45) | KMT2APOLBKDM4EALDH1A1HPGD | |
| SCHEMBL7958270 | 0.88 | SMN1; SMN2 (0.33) | KMT2ASMN1; SMN2 | |
| SCHEMBL7418615 | 0.88 | KCNK3 (0.45) | KMT2APOLBKDM4EALDH1A1HPGD | |
| SCHEMBL7964544 | 0.86 | KMT2A (0.42) | KMT2APOLBKDM4EALDH1A1HPGD | |
| SCHEMBL7418114 | 0.86 | SMN1; SMN2 (0.33) | SMN1; SMN2 | |
| SCHEMBL7957484 | 0.85 | POLB (0.45) | POLB | |
| SCHEMBL7961855 | 0.85 | SMN1; SMN2 (0.55) | KMT2APOLBKDM4EALDH1A1HPGD | |
| SCHEMBL7964298 | 0.83 | IGF1R (0.37) | KMT2AIGF1R | |
| SCHEMBL7418952 | 0.82 | RAB9A (0.44) | KMT2ASMN1; SMN2NTRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5639760-A | USEFUL AS MUSCLE RELAXANTS, SEDATIVES, ANXIOLYTICS, ANTICONVULSANTS, AND ANTIDOTES FOR DRUG OVERDOSE | MARYANOFF BRUCE E (US) | 1997-06-17 | — | — | US | claimed |
| US-6218384-B1 | FOR THERAPY OF ANXIETY, MUSCLE SPASMS, SLEEPLESSNESS, CONVULSIONS AND BENZODIAZEPINE OVERDOSES | ORTHO-MCNEIL PHARMACEUTICAL, INC. | 2001-04-17 | — | — | US | disclosed |
| US-5639760-A | USEFUL AS MUSCLE RELAXANTS, SEDATIVES, ANXIOLYTICS, ANTICONVULSANTS, AND ANTIDOTES FOR DRUG OVERDOSE | MARYANOFF BRUCE E (US) | 1997-06-17 | — | — | US | disclosed |