Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 2/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.34 |
| ▸ | WNT1 | P04628 | 1/20 | 0.33 |
| ▸ | MET | P08581 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7950067 | 0.88 | NPC1 (0.39) | — | |
| SCHEMBL7964531 | 0.87 | CSNK1D (0.40) | — | |
| SCHEMBL7961404 | 0.87 | EPHB3 (0.39) | — | |
| SCHEMBL7949787 | 0.86 | HTT (0.36) | CYP11B1CYP11B2 | |
| SCHEMBL7958270 | 0.83 | SMN1; SMN2 (0.33) | CYP11B1CYP11B2 | |
| SCHEMBL7964298 | 0.82 | IGF1R (0.37) | — | |
| SCHEMBL7418615 | 0.78 | KCNK3 (0.45) | — | |
| SCHEMBL7418401 | 0.78 | TP53 (0.39) | — | |
| SCHEMBL7964544 | 0.77 | KMT2A (0.42) | — | |
| SCHEMBL7420377 | 0.76 | EPHB3 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5639760-A | USEFUL AS MUSCLE RELAXANTS, SEDATIVES, ANXIOLYTICS, ANTICONVULSANTS, AND ANTIDOTES FOR DRUG OVERDOSE | MARYANOFF BRUCE E (US) | 1997-06-17 | — | — | US | claimed |
| US-6218384-B1 | FOR THERAPY OF ANXIETY, MUSCLE SPASMS, SLEEPLESSNESS, CONVULSIONS AND BENZODIAZEPINE OVERDOSES | ORTHO-MCNEIL PHARMACEUTICAL, INC. | 2001-04-17 | — | — | US | disclosed |