Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1D | P48730 | 1/20 | 0.40 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7957484 | 0.89 | POLB (0.45) | POLB | |
| SCHEMBL7420377 | 0.88 | EPHB3 (0.44) | — | |
| SCHEMBL7964433 | 0.87 | CYP11B1 (0.34) | — | |
| SCHEMBL7961766 | 0.86 | KMT2A (0.41) | CSNK1DCSNK1E | |
| SCHEMBL7418615 | 0.85 | KCNK3 (0.45) | POLB | |
| SCHEMBL7958240 | 0.83 | IKBKE (0.41) | — | |
| SCHEMBL7964125 | 0.83 | NTRK1 (0.43) | POLB | |
| SCHEMBL7964544 | 0.83 | KMT2A (0.42) | POLB | |
| SCHEMBL7949796 | 0.83 | RAB9A (0.44) | — | |
| SCHEMBL7413083 | 0.83 | HDAC1 (0.42) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5639760-A | USEFUL AS MUSCLE RELAXANTS, SEDATIVES, ANXIOLYTICS, ANTICONVULSANTS, AND ANTIDOTES FOR DRUG OVERDOSE | MARYANOFF BRUCE E (US) | 1997-06-17 | — | — | US | claimed |
| US-6218384-B1 | FOR THERAPY OF ANXIETY, MUSCLE SPASMS, SLEEPLESSNESS, CONVULSIONS AND BENZODIAZEPINE OVERDOSES | ORTHO-MCNEIL PHARMACEUTICAL, INC. | 2001-04-17 | — | — | US | disclosed |
| US-5639760-A | USEFUL AS MUSCLE RELAXANTS, SEDATIVES, ANXIOLYTICS, ANTICONVULSANTS, AND ANTIDOTES FOR DRUG OVERDOSE | MARYANOFF BRUCE E (US) | 1997-06-17 | — | — | US | disclosed |