Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | SYK | P43405 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MMP12 | P39900 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7980639 | 0.88 | SYK (0.44) | SYKNR3C2KCNH2ALDH1A1MMP12 | |
| SCHEMBL7977863 | 0.87 | SYK (0.39) | CYP1A2CYP3A4CYP2C9CYP2C19SYK | |
| SCHEMBL21400918 | 0.83 | NR3C2 (0.42) | SYKNR3C2KMT2APARP1ALDH1A1 | |
| SCHEMBL19250511 | 0.82 | NR3C2 (0.44) | SYKNR3C2KCNH2ALDH1A1MMP12 | |
| SCHEMBL7974822 | 0.80 | SYK (0.45) | CYP1A2SYKHTTNR3C2KMT2A | |
| SCHEMBL7977812 | 0.80 | NR3C2 (0.41) | SYKNR3C2KMT2ALMNAALDH1A1 | |
| SCHEMBL7977814 | 0.77 | NR3C2 (0.41) | SYKNR3C2KMT2AALDH1A1MMP12 | |
| SCHEMBL7977865 | 0.74 | NR3C2 (0.38) | NR3C2KCNH2LMNAPARP1ALDH1A1 | |
| SCHEMBL5260878 | 0.73 | KCNH2 (0.43) | NR3C2KCNH2 | |
| SCHEMBL12235340 | 0.71 | PARP1 (0.50) | NR3C2KCNH2PARP1MMP12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001030782-A2 | NOVEL HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2001-05-03 | — | — | WO | disclosed |