Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | NR3C2 | P08235 | 6/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21400918 | 0.82 | NR3C2 (0.42) | SYKALDH1A1MAPTNR3C2NR3C1 | |
| SCHEMBL7977814 | 0.79 | NR3C2 (0.41) | SYKALDH1A1MAPTNR3C2NR3C1 | |
| SCHEMBL619718 | 0.70 | NR3C2 (0.44) | ALDH1A1MAPTNR3C2NR3C1KMT2A | |
| SCHEMBL28473291 | 0.69 | ALDH1A1 (0.49) | ALDH1A1MAPTKMT2AMAOBCYP1A2 | |
| SCHEMBL23455714 | 0.69 | EP300 (0.42) | NR3C2NR3C1 | |
| SCHEMBL19629975 | 0.68 | MAPT (0.49) | MAPTNR3C2NR3C1KMT2A | |
| SCHEMBL3262979 | 0.68 | NR3C2 (0.47) | ALDH1A1MAPTNR3C2NR3C1KMT2A | |
| SCHEMBL21400859 | 0.68 | NR3C2 (0.47) | ALDH1A1MAPTNR3C2NR3C1KMT2A | |
| SCHEMBL8489674 | 0.67 | NPC1 (0.60) | KMT2ANFKB1NFKB2RELA | |
| SCHEMBL7244914 | 0.67 | ALDH1A1 (0.56) | ALDH1A1MAPTKMT2AMAOBCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001030782-A2 | NOVEL HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2001-05-03 | — | — | WO | disclosed |