Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 7/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | PGR | P06401 | 2/20 | 0.47 |
| ▸ | RORA | P35398 | 1/20 | 0.47 |
| ▸ | RORC | P51449 | 1/20 | 0.47 |
| ▸ | RORB | Q92753 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.46 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.46 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6579736 | 0.89 | KDM4E (0.53) | KDM4EALDH1A1GAAMAPTHSD17B10 | |
| SCHEMBL6579245 | 0.88 | KDM4E (0.56) | KDM4EALDH1A1GAAMAPTHTT | |
| SCHEMBL6581475 | 0.87 | KDM4E (0.47) | CNR2KDM4EALDH1A1GAAMAPT | |
| SCHEMBL6581473 | 0.87 | KDM4E (0.47) | CNR2KDM4EALDH1A1GAAMAPT | |
| SCHEMBL7980784 | 0.86 | KDM4E (0.47) | CNR2KDM4EALDH1A1GAAMAPT | |
| SCHEMBL6577102 | 0.84 | KDM4E (0.47) | CNR2KDM4EALDH1A1MAPTHTT | |
| SCHEMBL6577106 | 0.84 | KDM4E (0.47) | CNR2KDM4EALDH1A1MAPTHTT | |
| SCHEMBL6579397 | 0.82 | PDE5A (0.49) | CNR2KDM4EALDH1A1GAAMAPT | |
| SCHEMBL7974935 | 0.79 | KCNA3 (0.52) | CNR2KDM4EALDH1A1GAAMAPT | |
| SCHEMBL22042200 | 0.75 | MAOA (0.68) | CNR2KDM4EALDH1A1MAPTPLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6271416-B1 | O-(HYDROCARBONOXYACETAMIDO)BENZOIC ACID DERIVATIVES AS INTERMEDIATES | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-08-07 | — | — | US | disclosed |
| US-6136822-A | ETHER, HYDROXY QUINOLINONE COMPOUNDS | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2000-10-24 | — | — | US | disclosed |